Biliary cancer growth factor pathways, cyclo-oxygenase-2 and potential therapeutic strategies
نویسندگان
چکیده
منابع مشابه
Localization of cyclo-oxygenase-2 in human recurrent colorectal cancer.
AIM The aim of this paper is to examine COX-2 expression in human recurrent colorectal carcinoma tissues using immunohistochemistry and quantative real-time PCR (qPCR). METHODS Colon and rectal specimens were obtained from 26 patients with recurrent colorectal carcinomas. We examined COX-2 expression in human recurrent colorectal carcinoma tissues using immunohistochemistry and quantative rea...
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The central enzyme in the prostaglandin (PG) biosynthetic cascade is PGH2 synthase or cyclo-oxygenase (COX). At present, two distinct isoforms of PGH2 synthase/COX have been identified: COX-1 and COX-2. In many systems, COX-1 is a constitutively expressed isoform that is responsible for normal physiological production of PGs, whereas COX-2 is an inducible isoform that responds to cytokines, end...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 2001
ISSN: 0815-9319,1440-1746
DOI: 10.1046/j.1440-1746.2001.02438.x